The Midwest, often overlooked for its more mountainous counterparts, transforms into a rider's paradise as the leaves begin to turn. The sprawling hills, winding river valleys, and quiet backroads become a vibrant tapestry of color, offering a serene and beautiful escape from the everyday hustle. For me, riding has always been about finding that moment of pure presence, a feeling I first chased on dirt bikes as a tomboy and later found as a mother seeking a much-needed stress valve. The Midwest has a way of grounding you, and its fall scenery is nothing short of spectacular. While my husband and I are mostly day-trippers from our home in rural Ohio, we've found that these regions are perfect for a weekend escape or a longer journey. This article is your guide to five of the best fall motorcycle routes the Midwest has to offer, focusing on the breathtaking landscapes of the Ozarks and the iconic Great River Road. So, gear up, because it’s time to discover a different kind of beauty, a beauty that reveals itself on two and three wheels.

Ozark National Scenic Riverways Loop: Missouri’s Hidden Gem

Tucked away in the southeastern part of Missouri, the Ozark National Scenic Riverways offers a ride that feels like a well-kept secret. This area is less about high-speed runs and more about soaking in the natural beauty of spring-fed rivers, rugged bluffs, and dense forests. The roads here are a mix of state highways and county roads, often with gentle curves and scenic overlooks. A good starting point for a loop ride is Van Buren, Missouri, a small town that serves as the gateway to the riverways. From there, you can ride a loop that includes portions of Highway 103, Highway 60, and Route 19. The roads are generally well-maintained, but be prepared for some gravel on smaller side roads, a detail that riders on adventure bikes or three-wheelers can handle with confidence. You’ll be riding alongside the Current and Jacks Fork Rivers for a good portion of the trip, with plenty of opportunities to pull over and appreciate the scenery.

Must-Stop Spots & Local Flavors

One of the most impressive stops on this route is Alley Spring Mill, a picturesque red mill powered by a natural spring. The vibrant fall foliage provides the perfect backdrop for photos. For a bite to eat, check out The Landing in Van Buren. It’s a classic small-town diner that serves up a hearty breakfast and lunch. Further north, in Eminence, a stop at Two Rivers Restaurant for some local catfish is a solid choice. For lodging, consider the rustic charm of a cabin at Alley Spring Campground or the more traditional lodging at The Landing River Resort in Van Buren, which offers easy access to the river.

Great River Road: The Illinois Stretch

The Great River Road, or Great River Road National Scenic Byway, is a massive route that follows the Mississippi River for thousands of miles. The Illinois section, particularly from Alton to Grafton, is an incredible fall ride. This route, primarily on Illinois Route 100, is a smooth, winding ribbon of pavement with the majestic Mississippi River on one side and towering limestone bluffs on the other. The trees along the bluffs create a spectacular canopy of color, and the road itself is a joy to ride. You'll pass through quaint river towns and historic sites, with plenty of places to stop and enjoy the view. My husband, a two-wheel veteran, loves this stretch for its long, sweeping curves and stunning vistas.

Local Eateries and Scenic Overlooks

In Grafton, you’ll find Grafton Oyster Bar, which is a must-visit for seafood lovers. Their Cajun-style boils are a popular choice. Another great stop is Aerie’s Resort, which offers a chairlift ride up to a bluff-top restaurant with an incredible panoramic view of the river valley. For lodging, consider a stay at the Beall Mansion in Alton, a historic bed and breakfast that exudes old-world charm. Or, for a more modern stay with a view, look into the Tara Point Inn & Suites in Grafton, which is perched high on a bluff overlooking the river.

The Ozarks of Arkansas: Pig Trail Scenic Byway

The Pig Trail Scenic Byway, or Arkansas Highway 23, is a legendary ride that lives up to its quirky name. This route carves its way through the Boston Mountains, a rugged part of the Ozarks, and is known for its incredibly tight turns and dramatic elevation changes. This is a road that demands your full attention, and for those who love a technical ride, it’s pure heaven. The 19-mile stretch between Brashears and the junction of Highway 16 is particularly intense, a rollercoaster of twists and turns that feels like it was designed by a mischievous genie. The surrounding forest is dense and beautiful, and in the fall, it's a kaleidoscope of color. Riders on two wheels will appreciate the challenge, while those on a three-wheeler will feel the G-forces of every turn.

Pig Trail Pit Stops

A must-visit spot is Turner Bend, a small store and campground right on the Mulberry River. It’s a classic biker stop and a great place to stretch your legs and grab a cold drink. For lodging, the Wiederkehr Village offers a unique experience, a Swiss-style winery with a guesthouse that feels like you've been transported to the Alps.

The Great River Road: Wisconsin's Fall Colors

Heading north, the Wisconsin portion of the Great River Road offers a different flavor of fall beauty. From La Crosse to Prescott, Wisconsin Highway 35 hugs the river, providing breathtaking views of the bluffs and the water. This ride is a smooth, flowing journey with long, sweeping curves that are perfect for a relaxed pace. You’ll pass through charming towns like Alma and Pepin, with plenty of opportunities to stop and enjoy the small-town atmosphere. The highlight of this route is the stunning view from the top of the bluffs, where you can see for miles across the river valley, a truly majestic sight.

Places to Eat and Stay

In Alma, a visit to Alma Hotel & Tavern is a step back in time. The historic building and classic tavern feel are a great combination. For a treat, stop at Nelson Cheese Factory in Nelson for some fresh cheese curds. It’s a classic Wisconsin experience. For lodging, consider a stay at the Great River Bed and Breakfast in Alma for a cozy, intimate experience. For those looking for a more modern hotel, La Crosse has plenty of options, including the GrandStay Hotel & Suites.

Scenic Byway 155: The Ozarks of Oklahoma

Often overshadowed by its Missouri and Arkansas counterparts, the Oklahoma Ozarks offer a truly special riding experience. Scenic Byway 155, also known as the Talimena Scenic Drive, is a 54-mile journey that winds through the Ouachita Mountains on the border of Oklahoma and Arkansas. While technically a bit further south, its spirit is all Ozark. The road, which includes Oklahoma State Highway 1 and Arkansas Highway 88, is a masterpiece of engineering with switchbacks and long, flowing curves. The views from the various overlooks are incredible, with deep valleys and ridges covered in a sea of fall colors. This route is less populated than some of the others, giving you a chance to truly escape and enjoy the ride.

Dining and Lodging Along the Drive

While the drive itself is a bit remote, the towns on either end offer good options. In Talihina, Oklahoma, a local favorite is Pam's Diner for homestyle cooking and a hearty breakfast to start the day. In Mena, Arkansas, The Skyline Cafe has been a local favorite for decades, serving up classic American food. For lodging, the Queen Wilhelmina Lodge at the top of Rich Mountain is a must. The historic lodge offers breathtaking views and a comfortable place to rest after a long day of riding.

The Midwest in the fall is a testament to the fact that you don't need a mountain range to have an epic ride. The combination of stunning scenery, unique routes, and charming small towns makes for an unforgettable journey. Whether you’re on two wheels carving up the Pig Trail or cruising on a three-wheeler down the Great River Road, the fall season offers a special kind of magic that is just waiting to be discovered. So gas up the bike, pack your gear, and get ready to create some unforgettable memories.